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VP/VA Copolymer poly 1 vinylpyrrolidone co vinyl acetate pvp va64

VP/VA Copolymer poly 1 vinylpyrrolidone co vinyl acetate pvp va64

Brand Name: Slinmeng
Model Number: VP/VA64
MOQ: 25kg
Price: Negotiation
Payment Terms: Western Union,T/T,L/C
Supply Ability: 80 tons per month
Detail Information
Place of Origin:
China
Certification:
TDS, MSDS, COA
INCI:
VP/VA Copolymer
CAS No.:
25086-89-9
Appearance:
Whitepowder
N-Vinylpyrrolidone(%):
≤0.01
K Value:
26.0~34.0
Packaging Details:
25 kg/box
Product Description

VP/VA Copolymer poly 1 vinylpyrrolidone co vinyl acetate pvp va64


Description :

VP/VA copolymer (Pharmacopoeia name: copovidone) is a multifunctional excipient in the pharmaceutical industry, and its application is very specific and in-depth.

 

Technical Data:

Parameters

Value

Appearance

Whiteormilkypowder
Nitrogen content,(%)
7.0~8.0

pH(5%aqueous solution)

3.0~7.0
heavymetal,(ppm)
≤10

Arsenic,(ppm)

≤2

Lossondrying,%
≤5.0
Residueof ignition.%
≤0.05
N-vinylpyrrolidone(%)
≤0.01
Vinylacetateresidues(%)
≤0.01
KValue
26.0~34.0

 

Applications :

1. As a binder: An efficient and flexible molding assistant


  • Direct compression: This is its prominent advantage. As a dry binder, it can be mixed with active pharmaceutical ingredients and other excipients (such as microcrystalline cellulose) for direct compression into tablets. This eliminates the heating and drying steps of wet granulation, making it particularly suitable for drugs sensitive to moisture and heat. 
  • Wet granulation: The bonding efficiency of its ethanol or water/alcohol mixed solution is very high, and the resulting granules have strong compressibility. 

2. As a coating material: Forming multifunctional films


  • Rapid-release film coating: Mainly used to improve the appearance of tablets, mask the taste, prevent dust, and serve as an isolation layer for subsequent coatings (such as enteric coatings). Due to its excellent water solubility, it does not delay drug release. 
  • Process performance: Its solution has low viscosity, good spreading property, is easy to operate and form uniform films. 

3. As a sustained-release carrier: Solving the dissolution and release challenges


  • The core of enhancing the bioavailability of poorly soluble drugs: This is the most crucial application in current drug development. VP/VA copolymer is an ideal carrier for preparing amorphous solid dispersions. It "freezes" drug molecules in an amorphous state through hydrogen bonding and other interactions, preventing crystallization and thereby increasing the drug's dissolution rate and oral absorption by several times or even tens of times. 
  • For sustained-release preparations: When used alone, it mainly promotes release. However, when mixed with hydrophobic polymers (such as ethyl cellulose) in a specific ratio, it can form a composite matrix, which is used to prepare sustained-release tablets or to prepare sustained-release mini-matrices through hot melt extrusion technology, achieving continuous drug release.

 

Packaging specification:

25 kg/box. Other packaging requirements will depend on the actual situation.

 

Storage Period:

24 months in shade and seal for preservation.


Company Profile:

VP/VA Copolymer poly 1 vinylpyrrolidone co vinyl acetate pvp va64 0

Slinmeng (Guangzhou) New Materials Co., Ltd., headquartered in Guangzhou, China, is a provider of fine chemical solutions that integrates high-end customized production and global trade. The founding team has over 20 years of extensive experience in the fine chemical industry. With rich industry expertise, we have consolidated high-quality supply chain resources from various sectors to build a strong and stable supplier network, committed to providing customers with reliable supply assurance and highly competitive products.

VP/VA Copolymer poly 1 vinylpyrrolidone co vinyl acetate pvp va64 1

Slinmeng has a production workshop covering an area of over 8,000 and 5,000 standardized specialized warehouse for fine chemical raw materials.

 

FAQ:

1.Are you a factory or trading company?

We are a company integrating production and trade.No matter the products we manufacture or trade, high qualityproducts and competitive price always will be provided for you.

2.Do you provide free samples?

 Yes, we can offer free sample 100-200g , you just need to pay the freight .

3.What is your MOQ?

It depends on what you need. For most of our products, we offer flexible minimum order quantities, please contact us about specific details .

4. Is there a discount?

Discounts are based on the quantity you order, the largerthe quantity, the lower the price we can offer.

5.How long is your delivery time ?

Usually it takes about 5-10 days (for regular products) . If the quantity is large, the delivery time may be longer, depending on the actual delivery date of the factory.

6.Do you test all your goods before delivery ?

Yes, we have 100% test before delivery, and provide COA together .